Artificial intelligence (AI), machine learning (ML), and deep learning (DL) are highly popularized as tools to solve many problems in finance, computer security, natural language processing, and image processing. The use of these in cancer research has potential to reduce diagnostic time, improve detection, and potentially inform treatment. There are opportunities to scaffold learning with hands-on activities in the context of a societal problem to strengthen interest and persistence in STEM careers. Within ML, classification can be distilled to identification of features that are similar or different in a series of pictures. The game, “One of These Things (Is Not Like the Others)” popularized by Sesame Street, can be used to introduce students to this complex algorithm.
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